When I was going to University I took the bus most of my first year. I had problems with it just about every other day. There was no direct route to University, which wasn't a big problem. A simple transfer to another bus solves the problem. Unfortunately, the bus I had to transfer to rarely ever waited. Which meant a longer wait. Not a big problem but definitely annoying.
The buses would often be too early at the stop near me. I would get there 10 minutes BEFORE the bus was supposed to be there to find out that it had already been there.
One summer I worked in Burnside Industrial Park. There was no direct bus there. I would have to go all around town, and transfer 2-3 times, to get there. Add to that the bus that did run there ONLY ran once an hour. If you missed the bus you were screwed. From my nephew's experiences busing to work in Burnside it the service hasn't improved since then.
I will continue to drive instead of using Metro Transit if/when the strike is over.